Humalog is a diabetic drug also known as insulin Lispro and is an insulin analog that is used in treating type 1 and type 2 diabetes. Insulin is a hormone produced in the body naturally which helps the cells to take up insulin, break them down and convert it into energy.  When the production of insulin is reduced or stopped, insulin is supplied externally through injections or pumps.

Humalog is a kind of insulin that is injected subcutaneously to improve the insulin levels in the body and to break down sugars. It is insulin analog, meaning; the modifications are made in the structure of insulin to make sure they are absorbed into the body more quickly and to overcome any problem faced by the short-acting insulin. Since these medicine/solutions can be absorbed quickly they can be administered even within 15 minutes of meal without causing any hypoglycemia which can be the case with normal insulin.

Types of Humalog medicines

These medicines are of two types:

1. Humalog or insulin lispro

These are quick-acting insulins that start working within 15 minutes of injection and reach a peak within 90 minutes and works for less than five hours after administration.

2. Humalog Mix

This medication is a mix of both long-acting and short-acting insulin that helps it to act for longer periods of time inside the body. This reduces the task of injecting oneself frequently. It has a mix of a fish protein called protamine and insulin lispro which has a cloudy appearance. Make sure to remix the solution before using them.

They are available in two doses: U-100 (100 units per milliliter) and U-200 (200 units per milliliter).

These medications are not generally given to children with type II or type I diabetes.

How does it work?

The amino acid sequence proline at B-28 and lysine at B-29 present on the C terminal end of the B chain are switched. This change in the positions of amino acids helps them mimic the structure of the insulin-like – growth factor 1. This results in the modification of the structure of the protein which helps block the formation of insulin dimers and hexamers, which in turn helps the production or availability of a large amount of insulin in a short period. This change in the structure of insulin makes the Humalog insulin to be able to be absorbed in a short period of time and more quickly.

Some of the differences between analog insulin and normal insulin

  • They are faster to release and to come into action.
  • They do not require much waiting period before or after the meal.
  • They have a shorter duration of action thus preventing postprandial hypoglycemia.

Some of the side effects that can be seen after using Humalog

  • There can be a drop in blood sugar causing low blood sugar levels.
  • Can cause throat irritation, stuffy nose
  • Itching
  • Can cause flu-like symptoms
  • Cough
  • Can result in reactions at the injection site
  • Headache
  • Weight gain or abnormal distribution of fat

These symptoms are rare and are not commonly seen. If seen, make sure to visit the doctor. You can get the Humalog coupon code online to order this diabetic drug.